Wellsprings 20-1 is the same formula as Wellsprings Serenity with the addition of two natural oestrogen hormones, Estriol 0.11%, Estradiol 0.01%. The natural progesterone content remains at 2.34%.
Most women will use either Serenity or 20-1 cream, depending on whether they need additional oestrogen support. However, the two creams can be used together if you need only a small amount of oestrogen — see Can I use Wellsprings 20-1 at the same time as Wellsprings Serenity? for guidance on how to alternate between them.
Should I use Wellsprings 20-1 instead of Wellsprings Serenity?
